Cooperative functioning between antifreeze glycoproteins.
نویسندگان
چکیده
منابع مشابه
Antifreeze glycoproteins from Arctic fish.
Four species of fish in the Barents Sea of the Arctic, north of Norway and Russia, were caught and examined for the presence of antifreeze proteins in their blood sera. Only one species of Arctic fish, the polar cod (Boreogadus saida), was found to contain an antifreeze protein. Antifreeze glycoproteins were isolated and characterized from the blood serum of the Arctic fish, and their structure...
متن کاملAntifreeze Glycoproteins from an Antarctic Fish
A quasi-elastic light-scattering technique was used to study the hydrodynamic conformations of antifreeze glycoproteins from an Antarctic fish. Antifreeze glycoprotein is composed of repeating units of Ala-Ala-Thr, with each threonine O-linked to a disaccharide, and it exists as several polymers of different numbers of this repeating unit. Molecular weights of the two major active polymers are ...
متن کاملDirect Observation of Postadsorption Aggregation of Antifreeze Glycoproteins on Silicates
The adsorption of antifreeze glycoproteins (AFGP) from aqueous solution onto two different silicate minerals, muscovite mica and amorphous silica-titania, has been directly observed for the first time in situ using atomic force microscopy (AFM) and optical waveguide lightmode spectroscopy (OWLS). The former yields the lateral distribution and heights of adsorbed single molecules and massed adso...
متن کاملAntifreeze glycoproteins inhibit leakage from liposomes during thermotropic phase transitions.
Antifreeze glycoproteins (AFGPs), found in the blood of polar fish at concentrations as high as 35 g/liter, are known to prevent ice crystal growth and depress the freezing temperature of the blood. Previously, Rubinsky et al. [Rubinsky, B., Mattioli, M., Arav, A., Barboni, B. & Fletcher, G. L. (1992) Am. J. Physiol. 262, R542-R545] provided evidence that AFGPs block ion fluxes across membranes...
متن کاملDe Novo Gene Evolution of Antifreeze Glycoproteins in Codfishes Revealed by Whole Genome Sequence Data
New genes can arise through duplication of a pre-existing gene or de novo from non-coding DNA, providing raw material for evolution of new functions in response to a changing environment. A prime example is the independent evolution of antifreeze glycoprotein genes (afgps) in the Arctic codfishes and Antarctic notothenioids to prevent freezing. However, the highly repetitive nature of these gen...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1978
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(17)37970-x